What is Mangosteen?
The mangosteen (Garcinia Mangostana) is
a tropical fruit considered to be one of the finest tasting fruits in the world and has earned the popular title "the Queen
of Fruit." The mangosteen tree is found predominantly in Southeast Asia in countries like Cambodia, China, Indonesia, Malaysia,
Singapore, Taiwan and Thailand.
The fruit itself consists of the following
Pericarp (sometimes spelled Pericarb): A thick dark purple, smooth
rind that encloses the fruit segments.
Pulp: 4 to 8 triangular segments of snow-white, soft flesh. Known for
its excellent flavor, the mangosteen is proclaimed by many to be the best among tropical fruits.
What are Xanthones?
Xanthones are a class of plant derived
nutrients or "phytonutrients." They have been demonstrated in numerous scientific studies to hold tremendous nutritional value.
Found to exhibit strong antioxidant activity xanthones disarm free radicals in the body and enhance and support your body's
immune system. Although xanthones exist in small amounts throughout nature, it is found in concentrated amounts in the Pericarp
of the mangosteen fruit.
There are over 20 known forms of xanthones
naturally occurring in the Pericarp, the two most widely studied are Alpha Mangostin and Gamma Mangostin.
If xanthones from mangosteen are
so powerful, why haven't I heard about them?
The people of Southeast Asia are very familiar
with the prized mangosteen fruit and Asian Health Practitioners have long made use of Pericarp for a myriad of nutritional
uses. The mangosteen fruit, however, has never been introduced to the Western world and much of the science behind xanthones
is predominantly available to those in the medical community until recently. Many of the research studies on xanthones
have been done in universities and testing facilities throughout Asia and have recently started to catch the attention of
What is the most potent source
According to the research, the most concentrated
source of xanthones found in nature is in the Pericarp (rind) of the mangosteen fruit. The majority of clinical studies on
xanthones specify that the xanthones used were from the mangosteen Pericarp.
Does the world need another
Absolutely! The science of nutritional
supplements is still very young. New studies are constantly being released leading us to better solutions to today's health
concerns. More and more science continues to surface about xanthones and their incredible benefits to the human body and their
ability to support a wide variety of health concerns.
Every industry from automobiles to computers
constantly creates better ways to improve upon their products. Xanthones represent the very latest that nutritional
science has to offer. Much more than a great antioxidant, xanthones are a class of multi-functional phytonutrients poised
to raise the bar in the nutritional arena! At our company, we've not only launched a category creator, we
are the next generation of supplementation.
What are some of the studied benefits
Studies have demonstrated that xanthones
have the ability to offer support in the following areas:
Cholesterol concerns 1,2
Inflammation/pain response/Cox 2 inhibition 3
Skin conditions 4
Microbiological balance 5
Allergy support 6
Immune system support 7
1. Free Radic Res 2000 Nov;33(5):643-59.
Inhibition of lipoprotein oxidation by prenylated xanthones derived from mangostin. Mahabusarakam W, Proudfoot J, Taylor W,
Croft K. Chemistry Department, Prince of Songkla University, Hat Yai, Thailand.
2. Williams P, Ongsakul M, Proudfoot
J, Croft K, Beilin L. 1994. Mangostin inhibits the oxidative modification of human low density lipoprotein. Free Rad Res.
3. Biochem Pharmacol 2002 Jan 1;63(1):73-9.
Inhibition of cyclooxygenase and prostaglandin E2 synthesis by gamma-mangostin, a xanthone derivative in mangosteen, in C6
rat glioma cells. Nakatani K, Nakahata N, Arakawa T, Yasuda H, Ohizumi Y. Department of Pharmaceutical Molecular Biology,
Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba-ku, 980-8578, Sendai, Japan.
4. Farnsworth N. 1992. Thai Medicinal
Plants. Bangkok, Thailand: Medicinal Plant Information Center, Faculty of Pharmacy, Mahidol University.
5. Planta Med 1983 May;48(1):59-60.
Antimicrobial activities of Garcinia mangostana.
Sundaram BM, Gopalakrishnan C, Subramanian
S, Shankaranarayanan D, Kameswaran L.
6. Inhibitions of histamine release
and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant.
Nakatani K, Atsumi M, Arakawa T,
Oosawa K, Shimura S, Nakahata N, Ohizumi Y. o Department of Pharmaceutical Molecular Biology, Graduate School of Pharmaceutical
Sciences, Tohoku University, Sendai, Japan.
7. J Med Assoc Thai 1997 Sep;80
Suppl 1:S149-54. Immunopharmacological activity of polysaccharide from the pericarb of mangosteen garcinia: phagocytic intracellular
killing activities. Chanarat P, Chanarat N, Fujihara M, Nagumo T.
Department of Clinical Microscopy,
Faculty of Associated Medical Sciences, Chiang Mai University, Thailand.
8. Peres V, Nagem T, Faustino de
Oliveira F. 2000. Tetraoxygenated naturally occurring xanthones. Phytochemistry. 55:683-710
I eat a balanced diet.
Am I getting xanthones from my food?
No. The xanthone family of phytonutrients
can be found in trace amounts in certain fruits and vegetables, however, the pericarp of the mangosteen is the premier source
where these nutrients are found in concentrated amounts. Most scientific studies actually name the mangosteen pericarp as
the quintessential source of xanthones.
What makes xanthones from mangosteen
What is amazing is that the Mangosteen
(which, by the way, has no connection with the mango), has never been utilized for its multiple health benefits in North America
or Europe despite its history and popularity as a folk remedy in Asia and South America. Until recently, it has been one of
Nature's best kept secrets.
For centuries the traditional medical healers
of India, China, Malaysia, Thailand the Philippines and Vietnam have employed Mangosteen for its health benefits. In the last
150 years the plant has been transported to Africa, the Caribbean, Australia and South America where both researchers and
medical practitioners alike have studied and utilized its healing and protective properties.
What is meant by "whole fruit puree"
The mangosteen fruit pulp is delicious
and by itself holds some nutritional value, however, the pericarp and the seeds are the main source of a phtyonutrient known
as xanothones. The highest quality mangosteen juice products must utilize the whole fruit puree, where they have milled
the entire fruit-pulp, seeds and pericarp together -- thus capturing the full abundance of nutritional support.
This is essential because xanthones are
quickly being recognized as the newest superstar of the phtyochemical world and only a whole fruit process will
produce a only dietary supplement to feature this powerful component!
Are there any commercial items
Beware of products that use mangosteen
only as a flavor or only include the pulp (and not the pericarp). As aforementioned, the mangosteen fruit pulp is delicious
and there may be a few commercial items that feature the mangosteen fruit pulp or flavor, but only the whole fruit goodness
of the mangosteen — pericarp, pulp and seeds — will provide the full nutritional and healing value of mangosteen
Occasionally gift companies will ship frozen
mangosteen in for use in exotic gift baskets. These companies charge a premium price for the fruit. It is rumored
that the famous Harrods department store in England brought mangosteen in and charged the equivalent of several US dollars
for each piece of fruit.